About this Medicine article

The European Organization for Research and Treatment of Cancer QLQ-C30: A Quality-of-Life Instrument for Use in International Clinical Trials in Oncology by N. K. Aaronson; S. Ahmedzai; B. Bergman; M. Bullinger; A. Cull; N. J. Duez; A. Filiberti; H. Flechtner; S. B. Fleishman; J. C. J. M. d. Haes; S. Kaasa; M. Klee; D. Osoba; D. Razavi; P. B. Rofe; S. Schraub; K. Sneeuw; M. Sullivan; F. Takeda is a Medicine article available to read on EtoBox.

Background: In 1986, the European Organization for Research and Treatment of Cancer (EORTC) initiated a research program to develop an integrated, modular approach for evaluating the quality of life of patients participating in international clinical trials. Purpose: We report here the results of an international field study of the practicality, reliability, and validity of the EORTC QLQ-C30, the current core questionnaire. The QLQ-C30 incorporates nine multi-item scales: five functional scales (physical, role, cognitive, emotional, and social); three symptom scales (fatigue, pain, and nausea and vomiting); and a global health and quality-of-life scale. Several single-item symptom measures are also included. Methods: The questionnaire was administered before treatment and once during treatment to 305 patients with nonresectable lung cancer from centers in 13 countries. Clinical variables assessed included disease stage, weight loss, performance status, and treatment toxicity. Results: The average time required to complete the questionnaire was approximately 11 minutes, and most patients required no assistance. The data supported the hypothesized scale structure of the questionnaire

Author

N. K. Aaronson; S. Ahmedzai; B. Bergman; M. Bullinger; A. Cull; N. J. Duez; A. Filiberti; H. Flechtner; S. B. Fleishman; J. C. J. M. d. Haes; S. Kaasa; M. Klee; D. Osoba; D. Razavi; P. B. Rofe; S. Schraub; K. Sneeuw; M. Sullivan; F. Takeda

Publisher

Oxford University Press (OUP)

Published

1993

Language

EN

Field

Medicine (Health Sciences)