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Validation of Clinical Classification Schemes for Predicting Stroke: Results From the National Registry of Atrial Fibrillation by Brian F. Gage; Amy D. Waterman; William Shannon; Michael Boechler; Michael W. Rich; Martha J. Radford is a Medicine article available to read on EtoBox.

Context Patients who have atrial fibrillation (AF) have an increased risk of stroke, but their absolute rate of stroke depends on age and comorbid conditions. Objective To assess the predictive value of classification schemes that estimate stroke risk in patients with AF. Design, Setting, and Patients Two existing classification schemes were combined into a new stroke-risk scheme, the CHADS 2 index, and all 3 classification schemes were validated. The CHADS 2 was formed by assigning 1 point each for the presence of congestive heart failure, hypertension, age 75 years or older, and diabetes mellitus and by assigning 2 points for history of stroke or transient ischemic attack. Data from peer review organizations representing 7 states were used to assemble a National Registry of AF (NRAF) consisting of 1733 Medicare beneficiaries aged 65 to 95 years who had nonrheumatic AF and were not prescribed warfarin at hospital discharge. Main Outcome Measure Hospitalization for ischemic stroke, determined by Medicare claims data. ## Results During 2121 patient-years of follow-up, 94 patients were readmitted to the hospital for ischemic stroke (stroke rate, 4.4 per 100 patient-years). As indicat

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Author
Brian F. Gage; Amy D. Waterman; William Shannon; Michael Boechler; Michael W. Rich; Martha J. Radford
Publisher
American Medical Association (AMA)
Published
2001
Language
EN
Field
Medicine (Health Sciences)