About this nonfiction
The Prevention and Treatment of Missing Data in Clinical Trials by Panel on Handling Missing Data in Clinical Trials, Committee on National Statistics, Division of Behavioral and Social Sciences, National Research Council of the National Academies is a nonfiction available to read on EtoBox.
Randomized Clinical Trials Are The Primary Tool For Evaluating New Medical Interventions. Randomization Provides For A Fair Comparison Between Treatment And Control Groups, Balancing Out, On Average, Distributions Of Known And Unknown Factors Among The Participants. Unfortunately, These Studies Often Lack A Substantial Percentage Of Data. This Missing Data Reduces The Benefit Provided By The Randomization And Introduces Potential Biases In The Comparison Of The Treatment Groups. Missing Data Can Arise For A Variety Of Reasons, Including The Inability Or Unwillingness Of Participants To Meet Appointments For Evaluation. And In Some Studies, Some Or All Of Data Collection Ceases When Participants Discontinue Study Treatment. Existing Guidelines For The Design And Conduct Of Clinical Trials, And The Analysis Of The Resulting Data, Provide Only Limited Advice On How To Handle Missing Data. Thus, Approaches To The Analysis Of Data With An Appreciable Amount Of Missing Values Tend To Be Ad Hoc And Variable. The Prevention And Treatment Of Missing Data In Clinical Trials Concludes That A More Principled Approach To Design And Analysis In The Presence Of Missing Data Is Both Needed And Pos
It is typically read by self-directed learners exploring a subject in depth.
Common subject areas: history, science, philosophy, social sciences.
- Author
- Panel on Handling Missing Data in Clinical Trials, Committee on National Statistics, Division of Behavioral and Social Sciences, National Research Council of the National Academies
- Publisher
- National Academies Press
- Published
- 2010
- Language
- EN
- ISBN
- 9780309186513
- Category
- nonfiction
- Subjects
- Science, Technology, Medical